Description: Collie eye anomaly (CEA, Choroidal Hypoplasia-CH) is a hereditary eye disease in dogs, characterized by different level of impairment of the retina and choroid sclera that occurs during development of the eye. The inheritable disease is not progressive and the state after eye development remains stable. For this disease no drugs exist and it cannot be treated. The main symptom in affected dogs is hypoplasia (under development) of choroid, which is an important layer of the eye under the retina. In dogs with more extensive CEA disease the hypoplasia of retina or coloboma development may occur. The extent of this disease is different in each dog. Known symptoms range from mild to very severe that can lead to blindness.
Inheritance: autosomal recessive
Mutation: c.588+462_588+8260del7799bp in NHEJ1 gene
Sample: EDTA whole blood (1.0 ml) or 2 buccal brushes
The analysis is suitable for the following breeds: Afghan Hound, Australian Sheepdog, Bearded Collie, Border Collie, Great Dane, Hokkaido dog, Miniature American Shepherd , Miniature Australian Shepherd Nova Scotia Duck Tolling Retriever, Rough Collie, Shetland Sheepdog, Silken Windhound, Smooth Collie, Rough Collie
Notes: The analysis is performed by partner lab (SeekGenes) under Slovgen supervision. The invoice is issued by Slovgen. The result is sent to the customer from Slovgen lab.