Description: Muscular dystrophies are a group of hereditary degenerative disorders characterized by progressive muscle dysfunction. Clinical symptoms begin at the age of a few weeks and lead to severe progressive muscle weakness, which causes serious problems including gait and standing. Affected dogs also suffer from joint pain. In the posture, their spine is bent, the hind legs support the body and are placed under the abdomen. At the palpation, the atrophic muscles of the limbs can be felt. The hip, elbow and wrist joints have a visibly limited range of movement that is visibly very painful for them. There are problems with swallowing, regurgitation, salivation. Neurological examination revealed that males were more severely affected. Affected puppies are usually euthanized in the first year of age.
Inheritance: autosomal recessive
Mutation: c.289G>T in COL6A1 gene
Sample: EDTA whole blood (1.0 ml) or 2 buccal brushes. For official purposes, the confirmation of the dog’s identity by Veterinarian is recommended.
The analysis is suitable for the following breeds: Landseer