Description: NAD is a neurodegenerative disease affecting both the central and peripheral nervous systems of young adult Rottweiler dogs. Affected dogs show various neurological deficits including gait abnormalities, inability to stand (astasia), paralysis of limbs and so. Typical neurological symptoms such as blindness, strabism, impaired food intake may occur. A characteristic pathological manifestation is the swelling of axons the formation of spheroids developed and accumulated along axons throughout the brain and spinal cord.


Inheritance: autosomal recessive


Mutation: g.14777774T>C in VPS11 gene (CFA5)


Sample: EDTA whole blood (1.0 ml) or 2 buccal brushes


The analysis is suitable for the following breeds: Rottweiler