Description: The disease is one of many forms of inherited progressive retinal atrophy. This form of the disease occurs only in Smooth and Rough collies. The disease is characterized by progressive degeneration of photoreceptors (rods and cones) in the eye. The first changes in vision appear as night blindness at the age of six weeks. Clinical symptoms increase and at the age of six or eight months dogs with rcd2 disorder are functionally blind.
Inheritance: autosomal recessive
Mutation: 22 bp insertion in exon 4 of the RD3 gene
Sample: EDTA whole blood (1.0 ml) or 2 buccal brushes. For official purposes, the confirmation of the dog’s identity by Veterinarian is recommended.
The analysis is suitable for the following breeds: Rough Collie, Smooth Collie