Description:  Raine syndrome / Dental hypomineralization is a hereditary disease. It is characterized by insufficient mineralization during tooth development. This disease is associated with extensive tooth wear, tooth enamel cracking. May cause brownish spots or discoloration of the teeth, or inflammation of the pulp (pulpitis). Severe tooth wear can lead to chronic inflammation or even tooth loss. An abnormal dentine structure is observed in the histopathological examination and the enamel may be slightly hypoplastic.


Inheritance: autosomal recessive


Mutation: c.899C>T in FAM20C gene


Sample: EDTA whole blood (1.0 ml) or 2 buccal brushes. For official purposes, the confirmation of the dog’s identity by Veterinarian is recommended.


The analysis is suitable for the following breeds: Border collie