Description: Sensory neuropathy (SN) is a severe neurological disorder caused by degeneration of sensory and, to a lesser extent, motor nerve cells. Clinical symptoms occur between 2 and 7 months of age. This disease can result in impaired coordination, excessive strain and tic in the limbs, osteomyelitis, and can cause loss of pain perception, touch and temperature changes. The hyperextension of the limbs and self-mutilation wounds in the distal part of the limbs can occur. Degradation of axons and loss of nerve fibers are in affected dogs. There is very little chance of curing the affected individual because there are irreversible changes in the nerve fibers, which have lost the possibility of regeneration.

 

Inheritance: autosomal recessive

 

Mutation: 6,47 Mb inversion in FAM134B gene

 

Sample: EDTA whole blood (1.0 ml) or 2 buccal brushes. For official purposes, the confirmation of the dog’s identity by Veterinarian is recommended.

 

The analysis is suitable for the following breeds: Border Collie

 

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