Description: Hair length is one of the most important morphological traits in many dog breeds. Differences in coat length are visible in various dog breeds, but for some, the breed standard allows only one coat length. In some breeds, the long or short variant is inacceptable. One such example is Pembroke Welsh Corgis where longhaired dogs (also called “fluffy”) are unacceptable. Five recessive mutations (variants) in the fibroblast growth factor-5 (FGF5) gene are associated with the long hair phenotype in dogs. For simplicity, the variants are referred to as L, L2, L3, L4, L5, as indicated below.
p.Cys95Phe (L) is the most common among breeds.
c.578C> T (L2) occurs in Akita, Eurasier, Samoyed and Siberian Husky breeds.
c.556-571del16 (L3) occurs in Eurasian breed,
c.559-560dupGG (L4) occurs in Afghan Hound, Eurasier and French Bulldog
g.8193T> A (L5) occurs in the Afghan Hound.
Inheritance: autosomal recessive
Mutation: c.559-560dupGG in FGF5 gene
Sample: EDTA whole blood (1.0 ml) or 2 buccal brushes. For official purposes, the confirmation of the dog’s identity by Veterinarian is recommended.
The analysis is suitable for the following breeds: Afghan Hound, Eurasier and French Bulldog